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We dedicate this book to patients with inherited disorders whose
diagnostic odyssey is years long and often ends in unsatisfactory
treatments. We also hope our book will inspire young readers to train
in the field of genetic science and medicine where they can dedicate
their life to unraveling the mysteries of the genome.

Acknowledgments: The authors would like to thank William Gahl, clinical director of the
National Human Genome Research Institute and director of the Undiagnosed Diseases
Program, for his time and expertise. We also thank Anne Sophia Everett for reading an
early draft and offering feedback. We are grateful to the patients and their family members
who generously took time to answer our questions. We have changed their names to
protect privacy.

Text copyright © 2021 by Whitney Stewart and Hans C. Andersson, MD
All rights reserved. International copyright secured. No part of this book may be
reproduced, stored in a retrieval system, or transmitted in any form or by any means—
electronic, mechanical, photocopying, recording, or otherwise—without the prior written
permission of Lerner Publishing Group, Inc., except for the inclusion of brief quotations in
an acknowledged review.

Twenty-First Century Book
An imprint of Lerner Publishing Group, Inc.
241 First Avenue North
Minneapolis, MN 55401 USA
For reading levels and more information, look up this title at www.lernerbooks.com.
Main body text set in Metro Office.
Typeface provided by Linotype AG.

Library of Congress Cataloging-in-Publication Data
Names: Stewart, Whitney, 1959– author. | Andersson, Hans Christoph, 1956– author.
Title: Genomics : a revolution in health and disease discovery / Whitney Stewart and Hans
Andersson, MD.
Description: Minneapolis : Twenty-First Century Books, [2021] | Includes bibliographical
references and index. | Audience: Ages 13–18 | Audience: Grades 10–12 | Summary: “Since
the completion of the Human Genome Project, genetic studies has transitioned into
an era of discovery. This book explores the breakthroughs in research that inform our
understanding of ancestry, inheritance, epigenetics, health, and medicine.” — Provided by
publisher.
Identifiers: LCCN 2019041514 (print) | LCCN 2019041515 (ebook) | ISBN 9781541500563
(library binding) | ISBN 9781728401560 (ebook)
Subjects: LCSH: Genomics.
Classification: LCC QH447 .S74 2021 (print) | LCC QH447 (ebook) | DDC 572.8/6—dc23

LC record available at https://lccn.loc.gov/2019041514
LC ebook record available at https://lccn.loc.gov/2019041515
Manufactured in the United States of America
1-43699-33491-2/4/2020