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By studying peas, Mendel was able
         to effectively limit the number of
         variables, or aspects that changed                                                                                                     discover a pattern among these factors in successive   would always hide the other, “recessive” factor.
         from one phase to the next, and better                                                                                                 generations.                                          But the short, wrinkled, and white factors did not
         predict the outcomes.
                                                                                                                                                    Mendel began his experiments with a parent        disappear from the peas’ DNA. If a recessive factor

                                                                                                                                                generation, which he called P. He bred it and         appeared in two parent plants, their offspring
                                                                                                                                                called the next generation F1. All the F1 plants      might display it. Many years later, British biologist

                                                                                                                                                displayed the same factors. They were tall. Their     Reginald Punnett made a diagram to show the
                                                                                                                                                flowers were all purple. The peas themselves were     relationship between dominant and recessive

                                                                                                                                                all smooth. Things got interesting with the next      characteristics. It reveals why about one-fourth
                                                                                                                                                generation, called F2. About a quarter of the plants   of members of succeeding generations display

                                                                                                                                                were short, even though their parents were both       recessive characteristics.
                                                                                                                                                tall. The same proportions held true for smooth           Mendel worked with his pea plants for nearly

                                                                                                                                                and wrinkled peas, white and purple flowers, and      10 years. He published his findings in a relatively
                                                                                                                                                the other four factors. Mendel called factors such    obscure science journal in 1866. His work received

                                                                                                                                                as tall, smooth, and purple “dominant.” They          little attention—perhaps thanks, in part, to all
                                                                                                                                                                                                      the mathematical formulas included. Biologists

                                                                                                                                                                                                      of that era seldom delved into mathematics. After
                                                                                                                                                                                                      years of neglect, Mendel’s work was rediscovered
                                                                                                                                                            POINTING                                  in 1900. Several scientists, working independently,
                                                                                                                                                                  OUT
                                                                                                                                                                                                      confirmed what Mendel had written. Today, he is

                                                                                                                                                                                                      known as the “father of genetics.”
                                                                                                                                                          GREGOR MENDEL
                                                                                                                                                 Gregor Mendel grew up on a farm. He was a good           By then, other scientists had made related and
                                                                                                                                                 student who wanted to attend the best schools in the   important discoveries. Just three years after Mendel
                                                                                                                                                 region. But his family couldn’t afford it. He joined a   published his paper, Swiss biochemist Johann
                                                                                                                                                 monastery instead. The leader of the monastery sent   Friedrich Miescher made a startling discovery.
                                                                                                                                                 Mendel to the University of Vienna. That allowed
                                                                                                                                                 him to learn as much as possible about math and      His subject was far different from Mendel’s peas.
                                                                                                                                                 science, his favorite subjects. When he returned to   Miescher collected discarded, pus-filled bandages
                                                                                                                                                 the monastery, he began teaching at a local school.   from patients with serious infections. Washing
                                                                                                                                                 But Mendel wanted to make a name for himself.        off the pus, he was able to study lymphoid (white
                                                                                                                                                 He began his studies with pea plants. In later life, he
                                                                                                                                                 became the head of his monastery.                    blood) cells. He found a large, previously unknown
                                                                                                                                                                                                      molecule in the nucleus, or center, of the white





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