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Plagues in Civilization’s Early Cradles
               In the centuries following the emergence of farming and settled
               communities, the first large-scale civilizations appeared. They
               were nestled along the banks of large rivers in Mesopotamia (now
               Iraq), Egypt, India, and China, and modern historians call them
               the “cradles of civilization.” In those and nearby areas, epidem-
               ics of certain diseases repeatedly returned in cycles, generating
               understandable fear among local populations. In the late 1300s
               BCE, for example, in ancient Hatti (land of the Hittites, part of
               what is now Turkey), a scribe wrote, “What have you done O
               Gods? You have allowed a plague to enter the land of Hatti and
               all of it is dying! Now there is no one to prepare food and drink
               offerings for you! No one reaps or sows the gods’ fields, for the
               sowers and reapers are all dead! . . . The cowherds and shep-
               herds are all dead!” 8
                   The disease that caused that long-ago outbreak is unknown,
               as is that of another epidemic that struck China in the century
               that followed. A surviving Chinese document from the 1200s BCE
               worriedly asks, “Will this year have pestilence and will [there] be
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               deaths?”  Meanwhile, the Hebrew Old Testament, composed in
               the Middle East in the first millennium BCE, is filled with referenc-
               es to diseases afflicting society. Typical is the warning that those
               who disobey God will suffer from such ailments in a passage from
               Deuteronomy: “The Lord will smite you with consumption [tuber-
               culosis] and with fever, inflammation, and . . . [these ailments] will
               pursue you till you perish.” 10



               The 430 BCE Athenian Plague
               Very  little  detail  about  diseases  and  their  symptoms  in  such
               early ancient epidemics has survived. The first large-scale dis-
               ease outbreak that was extensively documented by a Greek
               historian was the so-called plague that struck the Greek city-
               state of Athens in the fifth century BCE. That historian was the
               Athenian chronicler Thucydides, who recorded the events of the



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