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INDEX


               AI (artificial intelligence), 41  stem cells. (see stem cells)  genetic engineering, 45, 67
                                     channelrhodopsin-2 (CR-2),
               biobots, 4, 6, 58        54–55, 57, 59     infographics, 24
               biological intelligence, 41  chemogenetics, 63–64.  brain, 64
                 ethics of, 42        (see also optogenetics)  DNA, 13, 45
               biomedical engineering, 4,   conditions and diseases  gene editing, 46
                   35–38              cancer. (see cancer)  retina, 56
                 advancements, 23     diabetes, 67        iPS cells (induced pluripotent
                 applications, 6      epilepsy, 33, 64       stem cells), 25, 30–31
                 careers in, 74–81    hemophilia, 53        as alternative to stem
               blindness, 14          Hunter’s syndrome, 53  cells, 12–13
                 artificial retinas, 5  lung disease, 25
                 channelrhodopsin-2 (CR -2),   Parkinson’s disease, 62  JCVI-syn3.0, 68–69
                   54–55, 57          quadriplegia, 35–36  magnetogenetics, 63.
                 and optogenics, 54–56  sickle cell disease, 47,   See also optogenetics
               brain-computer interface   53, 76          microbiota, 6, 65–66, 70–73
                   (BCI) technology, 5,   spina bifida, 18–21  Bacteroides, 70–71
                   32–33, 35, 38–42, 77  urea cycle disorder, 68–69  and pharmaceutical drugs,
                 BCI-VR, 36–37       CRISPR-Cas9, 46–48      67
                 brain to brain, 34, 43  and bacteria, 46–47  probiotics, 66–67
                 cost of, 37          clinical trials, 47   redesigned bacteria,
                 ethics of, 40–41     lab studies, 49–53     67–70
               brain implants, 36–39, 62, 78  risks, 50–51  synthetic bacteria, 67–69,
                 electroencephalograph                       72–73
                   (EEG), 33–35, 39, 43  de-extinction, 48
                 history of, 35      DNA (deoxyribonucleic acid),   neuroengineering, 5
                 and spinal cord injuries, 35  13, 48, 57, 61, 67–68,   ethics of, 40–41
               brain-to-brain, 34       73                Nobel Prize, 12
                                      copying, 47, 67, 69
               cancer, 6, 15, 19, 27–28  cutting, 44–45, 53  opsin, 57–59, 61, 63
                 CAR-T cell therapy, 52  editing, 46–47, 49–53  optogenetics, 54–55, 63
                 chemotherapy, 22, 52, 73  insertion, 44–45, 53, 59  blindness, 54–57
                 gene editing, 45, 49–51  sequences, 53, 67–68, 78  hearing loss, 62–63
                 radiation, 22, 52–53  drug development protocol,   memory, 54, 58–59
                 synthetic bacteria, 70,   28–29            pain management, 54,
                   72–73                                     59–62
               careers, 74–81        ethics and bioengineering,   organs, 18–31, 65
               cells, 4–6, 13, 16, 19–21,   12, 40–42       lab-grown organs, 4,
                   23–26, 28, 45–46,   gene-edited babies    19–21, 48
                   52–57, 60, 63–65,    scandal, 50–51      on-a-chip, 4, 27–31
                   67–70, 73, 79–80   gene editing, 49, 72  regeneration, 4, 7–9,
                 blood cells, 9–13, 17,   extracellular matrix (ECM),   15–16
                   47–49, 65–66         23–24               repair, 4
                 egg cells, 9–10, 22                        3D-printed, 19
                 muscle cells, 9, 11–12,   gene therapy, 45–46, 52–54,   transplants, 19–20, 25, 48
                   20, 58               62, 80              transplant shortage, 20,
                 skin cells, 9–12, 21–23  application, 51, 57, 59  26, 48







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